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Equivalent Sterilization Time at Different Temperatures

Calculates the equivalent holding time at a deviation temperature to achieve the same microbial lethality as a reference process using the Bigelow model.

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1. Define Input Parameters

2. Engineering Output

Temperature Difference Exponent (Exponent)
- -
Lethality Ratio (LethalityRatio)
- -
Equivalent Holding Time (t2)
- min

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Context & Assumptions

This calculation is essential in thermal process engineering for food and pharmaceutical sterilization. It allows engineers to compensate for temperature deviations during retort operations by adjusting hold times, ensuring the target lethality (Fâ‚€) is maintained despite process fluctuations. The method relies on the z-value, which characterizes the thermal resistance of the target microorganism.

Understand the Engineering Principles

Review the step-by-step derivations, typical industrial limits, and scale-up rules.

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